Research Breakthrough:
A UB-led research team has discovered that the protein NANOG, named after the Irish mythological land of youth, can reverse aging in skeletal muscle cells.
Interested in NANOG origin? According to a quick search: In Irish mythology, Tír na nÓg, often translated as the "Land of Youth," is a fabled island said to lie west of Ireland. This enchanting realm is known for its perpetual beauty and absence of aging and sickness, where time stands still and no one grows old. It is accessible only by invitation or by an arduous mystical journey. The most famous story associated with Tír na nÓg is that of Oisín, a warrior poet from the legendary band of heroes, the Fianna. Oisín is seduced by the beautiful Niamh, a princess of Tír na nÓg, and travels with her on a magical horse across the sea to her homeland. There, he lives a life of eternal youth and joy. However, his longing for home eventually overtakes him. Tragically, upon his return to Ireland, Oisín learns that centuries have passed, and touching the ground, he ages instantly, meeting his mortal end.
Findings: Experiments showed that overexpressing NANOG in senescent muscle cells improved characteristics associated with age-related deterioration, including autophagy and energy homeostasis.
Potential Implications: This research could lead to new treatments or therapies that help reverse cellular senescence, aiding those suffering from age-related disorders.
As we age, muscle mass naturally diminishes, a condition known as sarcopenia. However, certain lifestyle choices can significantly slow this process, ensuring strength and mobility well into our later years.
Firstly, resistance training is crucial. Engaging in activities like weightlifting or using resistance bands helps combat muscle loss by stimulating muscle protein synthesis. The American College of Sports Medicine recommends strength training exercises at least two times per week for older adults.
Equally important is nutrition. Protein intake is vital for muscle repair and growth. Older adults should aim for approximately 1.2 to 1.5 grams of protein per kilogram of body weight per day, as advised by the Academy of Nutrition and Dietetics. Sources like lean meats, eggs, and legumes are excellent choices. Additionally, ensuring adequate intake of omega-3 fatty acids, found in fish like salmon and in flaxseeds, has been shown to support muscle health.
Vitamin D also plays a pivotal role, particularly in aiding calcium absorption and bone health, which supports muscular function. Sun exposure and dietary sources like fortified milk or supplements can help maintain adequate Vitamin D levels.
Lastly, consistency is key. Regular physical activity combined with a balanced diet rich in essential nutrients can drastically reduce age-related muscle loss. Consulting with a healthcare provider or a nutritionist can also provide personalized guidance tailored to individual health needs.